442Varicella zoster virus infection after allogeneic hematopoietic cell transplantation in Korean children under relatively short-term acyclovir prophylaxis
نویسندگان
چکیده
transplantation in Korean children under relatively short-term acyclovir prophylaxis Seung Beom Han, MD; Jae Wook Lee, MD, PhD; Dong-Gun Lee, MD, PhD; NackGyun Chung, MD, PhD; Bin Cho, MD, PhD; Dae Chul Jeong, MD, PhD; Jin Han Kang, MD, PhD; Hack-Ki Kim, MD, PhD; Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Division of Infectious Diseases, Department of Internal Medicine, Collge of Medicine, The Catholic University of Korea, Seoul, South Korea
منابع مشابه
Varicella zoster virus infection after allogeneic hematopoietic cell transplantation in children using a relatively short duration of acyclovir prophylaxis
Although acyclovir prophylaxis against varicella zoster virus (VZV) infection for ≥1 year is recommended after allogeneic hematopoietic cell transplantation (HCT), the emergence of acyclovir-resistant viruses and adverse drug effects cannot be ignored. We investigated the cumulative incidence of VZV infection after allogeneic HCT in children receiving a shorter duration of acyclovir prophylaxis...
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Varicella-zoster virus (VZV) disease occurs in 30% of allogeneic hematopoietic cell transplant recipients who had a history of VZV infection. A safe and effective prevention strategy has not been established. In a double-blind controlled trial, 77 hematopoietic cell transplant recipients at risk for VZV reactivation were randomized to acyclovir 800 mg twice daily or placebo given from 1 to 2 mo...
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No consensus exists on whether acyclovir prophylaxis should be given for varicella-zoster virus (VZV) prophylaxis after hematopoietic cell transplantation because of the concern of "rebound" VZV disease after discontinuation of prophylaxis. To determine whether rebound VZV disease is an important clinical problem and whether prolonging prophylaxis beyond 1 year is beneficial, we examined 3 sequ...
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Infections of the central nervous system (CNS) with varicella zoster virus (VZV) is a rare occurrence after allogeneic hematopoietic stem cell transplantation. We herein report a case of VZV meningitis, radiculitis and myelitis that developed 8 months after cord blood transplantation, shortly after the cessation of cyclosporine and low-dose acyclovir. Although treatment with acyclovir did not a...
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To assess the incidence of and risk factors associated with postherpetic neuralgia (PHN) after hematopoietic cell transplantation (HCT) varicella zoster virus (VZV) infection, we conducted a retrospective chart review of 418 consecutive patients who underwent HCT between April 2005 and March 2007. The male/female ratio was 221/197, median age at HCT was 47 years (range: 0-69 years), and autolog...
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2014